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1-Isoquinolinol

puriss. p.a., matrix substance for MALDI-MS, ≥99.0% (HPLC)

Synonym:1-HIQ, 1-Hydroxyisoquinoline, Isocarbostyril
CAS Number:491-30-5
Linear Formula:C9H7NO
Molecular Weight:145.16
Beilstein Registry Number:9287130
EC Number:207-732-1
MDL number:MFCD00006899
PubChem Substance ID:24879392

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Description

ApplicationUsed as co-matrix with DNB for analysis of oligo­saccha­rides. Tolerant of buffers, salts, and sodium dodecyl sulfate (SDS).3
 Found to be more sensitive than DHB for analysis of high mannose N-linked glycans. Used in analysis of peptidoglcyan muropeptides.1,2

Properties

gradematrix substance for MALDI-MS
 puriss. p.a.
assay≥99.0% (HPLC)
mp212-216 °C
cation tracesBa: ≤5 mg/kg
 Ca: ≤20 mg/kg
 Cd: ≤5 mg/kg
 Co: ≤5 mg/kg
 Cr: ≤5 mg/kg
 Cu: ≤5 mg/kg
 Fe: ≤5 mg/kg
 K: ≤50 mg/kg
 Mg: ≤5 mg/kg
 Mn: ≤5 mg/kg
 Na: ≤200 mg/kg
 Ni: ≤5 mg/kg
 Pb: ≤5 mg/kg
 Zn: ≤5 mg/kg
abs.absorption/255 nm in accordance
 extinction/337 nm ≥2000

Safety

Personal Protective EquipmentEyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Safety Statements22-24/25
WGK Germany3

References

Cited Reference1. Xu, N., et al., , Structural characterization of peptidoglycan muropeptides by matrix-assisted laser desorption ionization mass spectrometry and postsource decay analysis. Anal. Biochem. 248, 7-14, (1997)
 2. Xu, N., et al., , Mercaptobenzothiazoles: A new class of matrices for laser desorption ionization mass spectrometry. J. Am. Soc. Mass Spectrom. 8, 116-124, (1997)
 3. Mohr, M.D., et al., , Matrix-assisted laser desorption/ionization mass spectrometry: improved matrix for oligosaccharides. Rapid Commun. Mass Spectrom. 9, 809-14, (1995) Abstract
BeilsteinBeil. 21,V,8,231